Current Issue

ICU patients have higher mortality with blood glucose level above 190 mg/dL

In-hospital mortality risk incrementally increased with every 10% rise in the range from 190 mg/dL to 250 mg/dL, according to a study of critically ill patients with and without diabetes in Chinese ICUs.

Statins may affect diabetes risk primarily in patients with prediabetes

There was a dose-response relationship between statin use and new diabetes diagnoses, with most cases seen in patients whose glycemic markers were close to the diagnostic threshold for diabetes at baseline, an individual-patient meta-analysis found.

About 5 in 1,000 U.S. adults have type 1 diabetes, 4 in 1,000 kids

In addition to a U.S. study assessing rates of type 1 diabetes in different age groups, a Swedish study looked at differences by age in whether patients' relatives also had the disease, finding that it was likely more tied to genetics in childhood-onset cases.

MKSAP Quiz: Hyperglycemia during hospitalization

This month's quiz asks readers to evaluate a 67-year-old man with hyperglycemia 3 days after admission for a COPD exacerbation. The patient's oral intake remains good.

Spotlight on limitations of the HbA1c test

A recent position statement called for use of one-hour glucose tolerance testing for diabetes diagnosis, a review described limitations of point-of-care HbA1c testing, and a study identified differences in the relationship between fasting glucose and HbA1c level by race, age, and sex.

State caps on insulin costs for commercially insured didn't increase insulin use

Limits on out-of-pocket costs did lower patients' insulin expenses, but the effect was mostly limited to those with health savings accounts, a pre-post comparison among U.S. states found.

In T2DM, periconceptional, noninsulin, second-line antidiabetes medications were not linked to major congenital malformations vs. insulin

A new study provides some reassurance to patients who unintentionally become pregnant while taking diabetes drugs but should be interpreted with caution because the number of infants exposed was low and only pregnancies resulting in live births were included, an ACP Journal Club commentary said.

In higher-risk, statin-intolerant adults with diabetes, bempedoic acid reduced MACE at a median 3 y

An ACP Journal Club commentary noted that it's unknown whether lower-risk and younger statin-intolerant patients would derive the degree of benefit from bempedoic acid found in this study, since the industry-funded trial enrolled only high-risk and older patients.